Buclizine HCl ( —— )

产品货号. M17929 CAS No. 129-74-8

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产品名称

Buclizine HCl
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities.
产品描述

Buclizine HCl is the hydrochloride salt form of buclizine, a piperazine histamine H1 receptor antagonist with primarily antiemetic and antivertigo activities. Buclizine binds to and blocks the histamine H1 receptor, thereby preventing the symptoms that are caused by histamine activity. Buclizine exerts its anti-emetic effect by binding to and blocking the muscarinic and histamine receptors in the vomiting center of the central nervous system (CNS). This may prevent activation of the chemoreceptor trigger zone (CTZ) and may reduce nausea and vomiting.
同义词

——
通路

Others
靶点

Other Targets
受体

HT; Cholinergic
研究领域

Others-Field
适应症

——

1. Mostafa GA, et al. Profiles Drug Subst Excip Relat Methodol, 2011, 36:1-33.

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